7/15/2023 0 Comments Download clarence the black lab![]() That's where the Black-6 family tree took root. Both were descended from a line of "fancy mice," sold as pets from a converted poultry farm in Granby, Mass., about 100 miles west of what now serves as the global headquarters for Charles River. He's talking about one that was created 90 years ago, when a mouse code-named C52 mounted one called C57 and deposited its semen in her reproductive tract with a waxy plug. When organizer Mark Moore says we have “a historic opportunity to systematically learn everything about a mammal for the first time,” he's not talking about just any mammal. And the $900 million project to knock out and test the effects of every last gene in the mouse, to create a vast, public warehouse of these tens of thousands of mutant lines-that's being done in Black-6, too. A rival breeder estimates that Black-6 accounts for half to two-thirds of its orders. ![]() ![]() Charles River won't break down its sales by strain, but a representative confirms that Black-6 mice outsell all others.
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